📃 Paper Title: Outcomes of Flexible Ureterorenoscopy for Solitary Renal Stones in the CROES URS Global Study
🧍 Author: Andreas Skolarikos
🕒 Year: 2015
📚 Journal: The Journal of Urology
🌎 Country: Greece
ㅤContext to the study:
Can you tell me about a study that reported the worse outcomes of Flexible Ureterorenoscopy for Larger Solitary Renal Stones?
ㅤ✅ Take-home message of study:
In patients undergoing flexible ureterorenoscopy (fURS) for a single renal stone:
Stone-free rate is worse for stones >20mm (31%) than for stones <10mm (91%) and 10-20mm (80%).
Overall complication rate is acceptable (6%), and there is no difference in overall complication rate by stone size, adjusting for body mass index (BMI).
ㅤ Prospective observational study
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Study participants:
Number included: 1210
Inclusion criteria:
18 years old with a solitary renal stone (>10 mm was defined as large stone).
Underwent fURS between January 2010 and October 2012.
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Key study outcomes:
Stone free rate (absence of stones or fragments > 1 mm) post fURS: 91% for stones <10mm; 80% for 10-20mm stones; and 31% for stones > 20mm.
Larger stones had longer operative time, longer hospital stay, were more likely to require re-treatment and to be re-hospitalised.
Overall complication rate 6%.
No significant difference in overall complication rate by stone size, adjusted for BMI.
Patients with a stone >20mm were at higher risk of a fever and a urinary tract infection post fURS than those with a stone < 10mm.
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Study Limitations:
Observational study.
Heterogeneity of participating centres, surgeons, and in the way stone-free rate was recorded.
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